Category Archives: July 2011

How we support our Progenesis users

We want all of our customers to get the most of their Progenesis software, and of course we want to help with any queries. The following support system has been designed to keep our users up and running and getting research data they can rely on. Coverwise When you buy a licence of Progenesis, it includes […]

How to choose the best reference run for data analysis with Progenesis LC-MS

“How do I know which reference run to choose for my proteomics data analysis?”. This is a question often asked by people new to Progenesis LC-MS and it’s a good one! Which reference run you choose has a major effect on the quality of run alignment and peak picking (feature detection), and therefore the reliability […]

Gas phase fractionation and Progenesis LC-MS: perfect partners

At this year’s annual meeting of the Proteomics Methods Forum, Dr Duncan Smith of the Paterson Institute for Cancer Research gave a very impressive presentation. By making some simple changes to his analysis techniques, he has massively increased his proteome coverage, as well as sequence coverage, when compared to traditional methods. And Progenesis LC‑MS is […]

Co-detection: The secret to reliably quantifying & identifying the same peptides on all your LC-MS runs

A question that we get asked by people new to Progenesis LC-MS is “why is the final list of proteins in my experiment exactly the same in every group?” The simple answer, and part of the power of Progenesis LC-MS, is co-detection. Co-detection is what we call our approach to peak picking based on an […]